Evil Genes

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Evil Genes Page 45

by Barbara Oakley


  DSM-IV (Diagnostic and Statistical Manual of Mental Disorders)

  defined, 47

  diagnostic criteria for personality disorders

  antisocial, 50–51

  borderline, 158–59

  narcissistic, 244

  distinction between Axis I and Axis II, 133–34

  exclusion of sadism from, 52

  explanatory listing of the ten Axis II personality disorders, divided into clusters A, B, and C, 134–36

  lack of connection with Machiavellianism, 47

  problems with “clinically significant” strategy for diagnosis, 162–63

  Duesberg, Peter (Inventing the AIDS Virus), denies standard treatment necessary for AIDS, 306n–307n

  Djukic, Slavoljub (Milosevic and Marković: A Lust for Power), 155

  Dunlap, “Chainsaw” Al

  presented Sunbeam as having stunning profitability when it was going broke, 294

  repulsive personality of, 30

  duplicity. See deceitfulness; gaslighting; lying; manipulation

  Durkheim, Emile, 50

  Duvalier, François “Papa Doc” (Haitian dictator), 286

  hypomanic qualities of, 314

  intelligence, enjoyment of torture, 311

  dyslexia, 57

  dysphoria in borderline personality disorder, 158

  eating disorders. See also Diana, Princess

  anorexia

  5-HT2A and, 71

  BDNF alleles and, 78

  borderline personality disorder and, 140

  Carolyn's, 142, 142n

  cognitive dysfunction, spiritual states, attempts to self-medicate and, 142n

  bulimia

  BDNF alleles and, 78

  borderline personality disorder and, 140

  serotonin transporters and, 73

  stress, genetics, and, 66

  Eden, Anthony (British prime minister), duped by Hitler, 315

  Effective, Efficient Professor, The (Philip Wankat), the importance of remembering names, 312

  effortful control, its heritability and relation to negative affectivity, 201

  Egan, Michael, work at NIH, 66–67, 363n9

  Einstein, Albert, Theory of Relativity was nearly named Invariance Theory, 322n

  Einzatgruppen, Nazi, 303n

  emergenesis (emergenic phenomena)

  general explanation of, 83–85

  of Machiavellian leadership, 314

  “emote control.” See also emotion

  borderline personality disorder and defaults in “emote control” system

  limbic system, 193–95

  overview, 193

  comprehensive discussion of various aspects of, 187–97

  defined, 187

  McCloskey, Jim, as an example of decision making using “emote control,” 188–89

  political partisanship and, 189–90

  role in abetting Machiavellians, 333

  emotion. See also “emote control”

  cerebral cortex and effect of, 181–82, 186

  delusional thinking and, 304

  evolutionary model for emotional behavior, 258–59

  executive control and, 199–202

  role in shaping “rational” thinking, 187–92

  role of limbic system in, 182–83, 186

  emotional contagion

  in Ceausescu's Romania, 270–71

  Enron's top-down mandated culture of greed, 295

  in Hitler's underlings, 305

  an increase in Machiavellians in a population could increase Machiavellian behavior in everyone through, 270–71

  in Stalin's underlings, 309

  worship of Mao, 242, 252

  emotional experience, deficient, as dimensional trait of psychopathy, 167

  emotionality. See affective instability

  empathy

  abstract reasoning and anterior cingulate cortex, relation to, 97–98, 100, 182

  lack of in personality disorders

  antisocial, 51

  borderline, 142, 149, 228

  narcissistic, 135, 244

  people

  Mao, 225–27, 227n

  Milosevic, 162, 166

  Stalin, 30

  psychopathy, 51, 56

  schizoid personality disorder, 135

  medial prefrontal cortex, role in, 99

  mirror neurons and, 104–105

  Williams syndrome's abundance of, 98–99

  emptiness, as DSM-IV diagnostic criteria for borderline personality disorder, 158

  “end justifies means” behavior, 204

  endophenotype. See phenotype, intermediate

  Engineering in Medicine and Biology Society, 211–12

  English speakers versus Chinese speakers, neurological differences of, 175–76

  Enron

  compared with sinister aspects of other groups, 30

  corrupt rise and fall of, 294–98

  difficulty in stopping Enron's illegal activities despite flagrant nature, 332

  environment, effect on personality. See nurture

  envy, 269

  a DSM-IV trait of narcissistic personality disorder, 244

  is possibly a useful, genetically linked trait, 269

  lack of in Alfred Russel Wallace, 292

  in Mao's China—creates danger and induces people not to be creative, 215

  Epstein, Brian, manic-depressive “drama queen” who launched Beatles, 291

  ethics

  imaging studies related to, 100

  systems of ethics can be ineffectual, even counterproductive, 335

  “Evening of Russian Poetry, An,” excerpt from Vladimir Nabokov's poem, 174

  evil

  allusion to possible benefits of, 32

  defined, 321–22

  and free will, 328–29

  genes (in that these genes can contribute to personality disorders as well as positive personality traits), 69–83, 85–87, 314–15

  older beliefs about personality and, 37–38

  questionable nature of Philip Zimbardo's conclusions about evil, described in The Lucifer Effect, 303n–304n

  some children born with marked (genetic) tendency toward, 57–58

  evolution

  Baldwinian, 263–64

  evolutionary benefits of psychopathic traits, 254–56, 387–88n2

  evolutionary model for emotional behavior, 258–59

  evolutionary perspective on borderline personality disorder, “psychiatrist Regina Pally,” 282

  general definition and discussion of, 65

  gradual development of rational as well as emotional capacities in humans, 187

  “human cultural and behavioral diversity can be understood in the same way as biological diversity” (David Sloan Wilson), 16

  Laura Betzig's Despotism and Differential Reproduction: preferential reproductive opportunities of Machiavellians, 268–70

  occurs much more quickly than had been supposed, 261–63

  executive attentional network

  anterior cingulate cortex and the, 182, 202

  Carolyn and her, 326–27

  Joseph Newman's work on psychopathy as a form of learning disability, 103, 326–27

  reticular activating system, poliovirus, and the, 114–16

  what of those who don't have ability to focus attention on self and change, 328–29

  executive control

  in clinical versus subclinical borderline personality disorder, 199–202

  coexisting borderline-schizotypal types show gray matter reduction in anterior and posterior cingulates, 227

  flowchart describing pathways of, 196

  role of DARPP-32 gene in, 82–83

  executive dysfunction in

  antisocial children and adults, 93–94

  borderline personality disorder, 232

  exhibitionism

  Mao's, 223–24

  narcissistic personality disorder and, 135

  of Shockley, William, Nobel Prize winner, 290
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  extroversion and D4DR, 82

  Eysenck, Hans J. (The Psychology of Politics), 46

  Fairbank, John, Harvard professor, as Mao's dupe, 241

  Fastow, Andrew, Machiavellianism trumps incompetence in CFO Fastow's rise and Enron's fall, 295–97

  father of author

  Alzheimer's disease of, 25, 114

  love for Carolyn, 122, 126, 323–25

  photographs of, 25, 123, 324

  Faustina, wife of Marcus Aurelius, 275, 275n

  fear

  and development of conscience, 95

  lack of in psychopaths and relation to genetics, 93

  serotonin transporters and inability to suppress, 74–75

  Williams syndrome phobias, 99

  Feynman, Richard: “you are the easiest person to fool,” 307n

  Fischer, Louis (Gandhi biographer), 298–299

  Fleishman, Jeffrey (journalist), description of defiant, arrogant Milosevic, 153

  forgiveness, affiliated with activation of specific areas of brain, 102

  framing lens, 176

  Frank, Anne, diary of, 27

  Frankfurter, Felix, Supreme Court Justice, on the Holocaust: “I cannot believe you,” 321

  Franklin, Rosalind, codiscoverer of structure of DNA, 290, 392n13

  free will and evil, 328–29, 330n

  “frequency dependence”

  allusion to (without use of term), 256

  discussion related to, 259–60

  Friedel, Robert O.

  Borderline Personality Disorder, Demystified, 136

  dimensional description of borderline personality disorder, 164

  discussion of borderline sister, Denise, 136

  Friedman, Russell, “You can't love someone into mental health,” 320

  Fukuyama, Francis (Trust), 219

  functional magnetic resonance imaging (fMRI) defined, 90

  Galileo, 306

  gambling, as addictive behavior, 233

  Gandhi, Mahatma

  “had a violent nature,” took pains to control, 298–99, 328

  hypomanic qualities and remarkable memory, 313

  as unsuccessful role model for Kosovar resistance against Serbs, 169

  gaslighting. See also lying; manipulation

  defined, 146–47

  as demonstrated by

  Hitler and his henchmen, 305

  Milosevic, 164–65

  dorsolateral prefrontal cortex and, 182

  etiology of term, 146n

  Gaslighting…(Theodore Dorpat), 147

  theta rhythms may be thrown off by, 148

  used as coping charactistic in

  antisocial personality disorder, 209

  borderline personality disorder, 137, 209

  used for successful manipulation and control, 147, 250–52

  Gates, Bill

  ability to argue competently with him is prized, 296n

  philanthropy (with Melinda Gates), 319

  temper, 300

  Gates, Melinda, philanthropy of (with Bill Gates), 319

  genes (alleles of genes are also listed here)

  alleles, explanation of, 63

  chromosome 17, illnesses associated with genes on, 64

  copy number variants, 63

  explanation of basics about, 60–65

  future reengineering of, 329–30

  and personality

  “evil” (in that these genes can contribute to personality disorders as well as to positive personality traits), 69–83, 85–87

  no single gene causes a personality disorder, 68

  older beliefs about personality and genes, 37–38, 38n

  overview of effect on personality, 59

  religious predisposition, 59, 59n

  poliovirus infects only those with certain genes, 111

  Quantitative Trait Loci (QTL) model, 71

  specific genes and alleles

  5-HT1B role in aggression, 71

  5-HT2A role in self-mutilation, anorexia, and suicide, 71

  5-HT3A influence on amygdala and reaction time, 71–72

  ASPM (cognition), 262

  BDNF, related to neural growth, 77–78

  clock, related to sleep cycles, 233

  COMT, “warrior” or “worrier,” 78–80

  D4DR and novelty seeking, extroversion, 82

  DARPP-32, intelligence and schizophrenia, 82–83

  MAO-A, helps break down neurotransmitters, 54, 80–82

  microcephalin (cognition), 262

  related to the enzyme tryptophan hydroxylase (TPH), 82

  related to the hormones vasopressin, oxytocin that help produce feelings of love, 83

  serotonin-related, 69–75

  stress's effect on, 65–66

  genetics. See also genes

  family discord flowing from, 60

  fundamental overview of, 60–65

  genetic drift, 65

  “genetic stamping,” large effect of certain historical individuals, 267–70

  “imaging genetics,” 67–69

  intermediate phenotype and, 66–69

  loss of olfactory and detoxification-related genes, 262, 262n

  of personality traits and disorders

  affective instability, heritability, 86

  impulsivity, heritability, 86

  lack of fear, 93

  narcissism (very strongly heritable), 244, 287

  negative affectivity and effortful control, 201

  psychopathy, 55–58

  sadism, 52

  schizophrenia and schizotypal personality disorder, 227

  separate heritability of borderline traits for mood disorders, impulsivity, and cognitive dysfunction, 206

  Williams syndrome, 99

  of susceptibility to polio, 111, 327

  various populations have genetics adapted to cold or to high altitudes, 262

  vitamin D and reshaping of genetics in northern climes, 263

  Wiener's theory of Jewish versus Christian traditions and effect on, 86–87

  genetic stamping, 267–68

  Genghis Khan

  and his roadies spread their genes, 267

  surprisingly benevolent and visionary leader, 286

  Genghis Khan and the Making of the Modern World (Jack Weatherford), a highpoint of compulsive biography inhalation, 286n

  genocide

  complicity of the United Nations in, 332

  do well-intentioned policies of appeasement lead to, 307

  Milosevic's role in, 156n, 162, 169–71

  occurs in part because people can't believe Machiavellians, with their neurologically based sinister underpinnings, exist, 321–22

  questionable nature of Philip Zimbardo's conclusions related to genocide, described in The Lucifer Effect, 303n–304n

  Samantha Power's “A Problem from Hell,” how and why genocide happens, 321

  genome

  defined and discussed, 62, 67, 68, 69n, 84

  human genome project, 34, 38, 290

  genotype, explanation of, 64

  Geoghan, John, pedophile priest, 107

  George, Bill, on Warren Buffet's profound effect on ethics in business, 319

  Giocangga, progenitor of Qing dynasty, and genetic stamping, 267

  Glad, Betty, “Why Tyrants Go Too Far,” 34

  Gladwell, Malcolm

  dark side of Blink and relation to “emote control,” 379n20

  strengths and weaknesses of imaging, 367–68n2

  “gold diggers,” 271–78

  Goldhagen, Daniel Jonah (Hitler's Willing Executioners), 303n

  gossip

  importance of “gossip” magazines in reporting on Machiavellians, 251

  “office gossip” and its role in alerting about Machiavellians, 337–38

  gray matter

  in autistics is increased, in pathological liars is reduced, 106

  differences in psychopaths’, 106

  loss with one form of schizophrenia, 205

>   Great Leap Forward, 226, 234–36

  “Great Society” legislation, 258

  Great Terror, The (Robert Conquest), or, I Told You So, You Fucking Fools, 28n

  guilt. See also empathy

  abstract reasoning, relation to, 100

  affiliated with activation of specific areas of brain, 102

  Guinness Book of World Records and Ismail the Bloodthirsty, 268

  gullibility. See naivete

  Halifax, Lord: “His virtues have done more harm than the vices of hundreds of others,” 292

  Hall, Matthew Henry: cartoon “You're the only peson in this department I trust,” 44–45

  Halliday, Jon (Mao biographer), 218–19, 239–40

  Hanks, Tom, in relation to neuroimaging study on partisanship, 189–90

  Hardy, Jason, Ashkenazi genetic mutations and intelligence, 87

  Hare, Robert

  comorbidity of psychopathy with other disorders, 168

  “corporate psychopaths,” 106, 108

  sadism's wider context, 53–54

  Harpending, Henry: Ashkenazi genetic mutations and intelligence, 87

  Harris, Judith Rich

  Harris's Nurture Assumption laid profound case for influence of genes on personality, 37, 175

  higher-status members of group have more influence, 270

  No Two Alike, 56n

  Hauser, Marc, studies of neurological features of morality, 322

  Heller, Leland, comments on mood swings in borderlines, 230

  heritability. See genetics and also individual personality disorders

  He Zizhen, Mao's third wife: difficult life ending in madness, 221–22, 226–27, 227n

  Hill, Christopher, Ambassador, 165

  Hilton, Paris, and family, 273, 337

  hippocampus

  in borderline personality disorder

  differences may explain hypersensitivity to emotional cues, 194, 206

  smaller, 194, 205

  differences in unsuccessful versus successful psychopaths, 105

  enlarged in London taxi drivers, 176

  illustrations of, 93, 101, 183

  murderers have “turbocharged,” 97

  portrayed in flowchart form (as “Hippocampal Formation”), 185, 196

  Historia Augusta, 274–75

  histrionic personality disorder

  defined, 135

  illustration showing overlap with borderline personality disorder, 208

  MAO-A in “cluster B” personality disorders, 80

  Hitchens, Christopher (The Missionary Position), 285

  Hitler, Adolf

  ability to dupe credulous, 315

  affective instability (rage), 299–300, 305

  brief overview compared to other dictators, 28, 298, 315

  control, desire for, 308–309

  extraordinary memory of, 311–12

  father's abuse, 218

  hypomanic qualities, 314

 

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