Sally lit a cigarette, frowning, and sat back in her desk chair. That was part of it, all right, but it wasn't that which set the bell jangling. Damn strange story, though—why report it at all? Unless the President was setting up some brownie points against something coming up. But what did set the bell jangling? She turned on a fan to cool her skin a little and sat chain-smoking for almost an hour, poking through the garbage can, begging the old subconscious to spit out something else. They'd certainly used a new drug in Colorado, but not without "preliminary testing," far too much risk of side effects, even in an emergency. . . .
Side effects. Sally dove into a thick file and pulled out a very brief item from the Denver Post. Several people from the Canon City area were repotting progressive visual disturbances following recovery from the plague infection there. Similar but not identical to retinitis pigmentosa. Also, a few had associated intention tremors—yeah, she knew all about that, her granddad had Parkinsonism. Thought to be cerebral side effects of some kind of plague toxin among those who survived the infection. Fine. But why did those people survive? Because they were fed a new antibiotic? If so, maybe the side effects were due to the antibiotic, not the infection. . . .
Still there was a hole, something missing. She knew she'd seen something, several weeks ago. She tried key words to see if she could spring anything. Names. Places. Something in there was on the right track. . . .
Fort Collins. That was it, a dateline, someplace in northern Colorado. A TV newsclip that she'd seen, some woman from the CDC working there—what was her name? Janrette ? Something like that—and they'd been testing a new antibiotic agent against the plague bug. What had hit Sally was how excited the woman had been, really high on this drug. They'd tested it against infected lab animals and it had been amazing, hit the bug hard and fast almost a hundred percent of the time, and no side effects of any kind. Safe as tetracycline, she'd said, two or three times. Half a dozen people in the lab there had taken it, too, to measure human blood levels and be sure of the no-side-effects bit. She'd recommended it for use in Canon City. . . .
Yes. That was it. Sally Grinstone sat back and smoked. That was what her subconscious had been worrying about and finally coughed up. First of all a splendid new drug, highly effective, a miracle drug right when they needed it. And then, suddenly, side effects, nasty side effects, people going blind, for God's sake, and Sealey Labs backing off from the President himself. . . .
Something stank.
Sally sat there a long time, more and more certain that something was wrong. She knew a little bit about drug testing. With any major toxic reaction, you either got it in the face right at the start, or you didn't get it at all, at least nothing big. Unless they had a bunch of blind Parkinsonian rats running around that lab in Fort Collins, Colorado, and just weren't talking about it. She looked at the telephone, started calculating the time difference to Denver—Maybe they stay up late out there—but shook her head. That's no good. You can't go for blood over the phone, it doesn't work. . . .
She heard Teddie padding out behind her, felt a touch on her shoulder, a kiss on her neck, a gentle hand cupping her breast.
"Honey?"
"Not now, sweet." Sally slipped to her feet. "Got to get some sleep. I've got a long trip tomorrow."
In cadence with the dull hoofbeats of the Horseman, plague moved relentlessly in on Savannah. At first people responded only slowly to Jack Cheney's public-health directives going out on the emergency Civil Defense radio and TV. For one thing, it was altogether too hot to pay attention; the scalding sun beat down every day in the longest, most merciless early September heat wave in recent memory, day after steaming day of 105-degree heat. Nobody stayed inside by the radio or TV in that kind of heat, especially in the long miles of stinking, heat-creaking frame tenements that stretched across the middle of the city, where air-conditioning was seldom to be found and then rarely, if ever, still working. There were few trees gracing those parts of the city, but the only breathable air was outdoors and the tenements themselves threw some shade, so people sat on their rickety porches, gazing at the heaps of trash and garbage in the vacant lots across the street, where the rats wended their way through their mazes of tunnels. When the afternoon thunderstorms would strike, the gutters would fill and overflow for a while and nobody would seem to notice how very many dead rats were washing down to the drainholes. And then, the storm's momentary coolness merely tantalizing, the streets would start steaming again in the afternoon sun and the dense, humid miasma of hot heavy air would press down upon them for the rest of the night.
The earliest response to the public-health warnings came, predictably, from the city's doctors, and they defined the problems that lay ahead. It came first from the crowded offices and free clinics in the vast tenement areas, then from the middle-class and upper-class doctor's offices and private clinics and group practices. Suddenly doctors everywhere were seeing a sharp influx of very sick people. Many became abruptly, devastatingly ill, spiking 105-degree fevers, shaking with chills, coughing and gasping and spitting into blood-filled handkerchiefs. Others—far fewer, but still some—were breathing all right but presenting more classical symptoms: septicemic shock and prostration; great ugly, swollen purple-black lumps under their arms and in the groin; nausea and sudden uncontrollable vomiting; all the marks of the raging toxicity as the bacteria spread and grew.
They knew what they were seeing, the doctors did, and they scrambled to get the vaccinations they had neglected to get a few days earlier for themselves and their nurses and receptionists—the old vaccine first and then, finally, finally, in a dribble that was earmarked first for medical workers only, a tiny supply of the new vaccine said to provide up to sixty percent protection from the mutated bacteria. But unfortunately, just knowing what they were dealing with didn't in itself tell the doctors what to do about it. Jack Cheney and his public health crew, aided by Carlos Quintana's CDC team, mounted a major effort early on to reach every doctor, lay out ground rules for handling the sick, mailing them photocopied guide sheets, bulletins, updates, but still the Health Department switchboards were flooded twenty-four hours a day with thousands of calls asking for specific advice—calls for information, supplies, directions—the demand billowed in from all parts of the city. Most doctors and their nurses made some sort of attempt at establishing isolation techniques in their offices. They all worked in gloves and gowns, caps and masks, and—short of urgent emergencies—some of them turned away all the patients who didn't have plague and sent them home in order to spare them possible exposure. Some clapped surgical masks on everybody who walked in the door. But at best, all such impromptu efforts proved terribly imperfect. What was worse, antibiotics and vaccine could not be improvised, and soon the tiny stockpiles of these vital necessities began dwindling. When more new vaccine came in, it immediately went out to the public-health workers, the police, the five-hundred member rat squad hastily mobilizing a rat-control program to hit the major concentrations of the vermin and all others trying to fight the epidemic's ravages, including the garbage men.
Especially the garbage men.
Their humble role in the infinite scheme of things was suddenly transformed as they found themselves needed just as urgently as the doctors. The pressing problem was: what to do with an ever-increasing number of bodies? Patients who had walked into doctors' offices were found dead on the waiting-room floor—with nobody around to claim the bodies. At first, aid cars were called to pack them off to the county morgue—but soon the morgue had bodies stacked up like cordwood, without til they could be disposed of. Every mortuary in town was overfilled with bodies; the crematoria were working to capacity and glowing cherry-red from the heat and still falling far behind. Finally, one day, a long, sad line of bulldozers were spied making their way out the old highway to the west, toward a large unimproved tract of city-owned land, where they began scooping out a vast sanitary landfill disposal site. While the mortuaries and crematoria fought to meet the needs of t
he paying customers, this huge city excavation was prepared to take care of the poor.
Well, a mass grave and landfill five miles outside the city limits was all well and good, but it did not solve the logistics of getting the bodies out there, and it was here that the garbage men found themselves impressed into an unaccustomed role. In the ghetto areas there was no place to put the bodies at all, so the dead would lie in state in their tenement beds until the dark hours of the night. And then the cousins, or uncles, or husky sons of the victims, their activities mercifully concealed from light of day, would perform the rites of transport to an empty lot a block away, or an alley strewn with overflowing trash cans, or a readily opened storm sewer, and the corpses would be deposited. And of course the ancient bond of silence prevailed: nobody saw anything, nobody heard anything and nobody knew who had done what.
Thus with the Coroner and the Mayor both backed to the wall, the garbage men were summarily appointed to act as a city death patrol. At first one or two garbage trucks a day, then three or four a day, departed from their usual rounds to weave up and down the streets and alleys, their motors and cranks and lifts rumbling a mournful threnody, performing their strange collection rites, then rolling on out the Old Highway through the swampy flats to the sanitary fill, soon known as Five Mile Dump, to lower the bodies to their final rest. And on days when the bulldozers did not get the day's produce fully buried before sundown, the rats were there to help, soon expanding into the most enormous colony of sick rats in all the sovereign state of Georgia, but nobody paid attention to this for quite some time. . . .
It was at this point that the public response to the plague began to undergo a sharp and distinctive change. With bodies to be tripped over in the streets each morning, and with more and more families bereaved of one or two or more members, people for the first time began to grasp the true nature of the disaster that was upon them, and they began to follow blind instinct in seeking safety. Ancient gut-wisdom declared that the familiar was safer than the strange, home safer than elsewhere, inside safer than outside. All over the city of Savannah people abandoned their streets and porches and fled inside, closing and barring their doors, slamming their windows and emerging only when forced to emerge. They huddled inside in the stifling heat and the smell of death and waited for something to happen, and the plague in Savannah moved on to a different, more sinister phase.
36
"You say she's coming here?" Frank Barrington said when he arrived in Fort Collins about six o'clock that evening and Monique told him what she had planned.
"No, not here," Monique said, looking around the small furnished apartment. "We're going to meet her for a drink at Barnaby's. It shouldn't take very long, I hope, and then we can shake her loose and come back here for some nice chops for dinner." She hesitated. "I probably shouldn't have bothered you at all," she said. "It just seemed so odd to have her calling, just after that grim little note from Carlos about the mess in Savannah and the fight they're having with Sealey about that medicine. And you know more about Canon City than I do; all I did was run the tests up here and report what happened—"
Frank put a finger on her lips. "Stop apologizing. It's only eighty miles up here from Golden. I can drive that anytime, and I'm getting bored with this weekend visitation crap, anyway."
She smiled. "Bored with me?"
' 'Bored with being eighty miles away. I'm either going to get myself assigned up here or start commuting." He kissed her. "This woman that called . . . You say she's some kind of detective?"
"She's an investigative reporter, which is something else. She writes for the Philadelphia Inquirer. She called from Denver at seven-thirty this morning and she's turning up at Barnaby's in thirty minutes."
"So what does she want with you?"
Monique shrugged. "I'm not quite sure. Said she was checking some things about the Colorado outbreak, but she got very vague about just what." She saw Frank's cloudy expression and smiled. "Don't worry, sweet. We'll meet her and have a nice drink and play it close to the vest, and everything will be all right. I've dealt with these people before."
"If she acts like that TV woman," Frank said, "I'll break her arm."
As it turned out, Sally Grinstone was not quite the horsey, aggressive female newsperson Frank had been visualizing. Aside from a pair of veiy sharp and penetrating eyes, Sally Grinstone looked for all the world like an overchubby, slightly untidy teen-age kewpie sitting there in the booth at Barnaby's, sipping some colorless drink and chainsmoking cigarettes, her breasts quivering a little with every movement, her hair done up carelessly in an incredible double ponytail. Hardly anything threatening about her, Monique thought, except for the air of slightly spurious innocence. No tape recorder on the table, either, Monique noticed. "You're not taping this?" she said as she and Frank slid in across the table.
"No need to," Sally said. "This is just background, a couple of points to clear up. Doesn't even need to be on the record, if you'd rather not." She spread her hands. "I'm not even sure what I'm looking for, just yet—maybe you can tell me. You're Monique Janrette?"
"Jenrette," Monique said.
"That's right. I've seen quite a number of your papers," Sally said, and Monique had the sudden odd feeling that maybe this girl actually had. "Look, I'm here because some things have me puzzled and I hope maybe you can help me clear them up. You've heard about Sealey Lab's decision on their new antibiotic?"
"I've heard they're dragging their feet about supplying it," Monique said cautiously.
"They've pulled it out of production altogether, as of five p.m. yesterday," Sally said. "It was on all the wire services. They're calling back all outstanding supplies, including supplies for all experimental protocols." She leaned across the table. "Now what do you think of that?"
"I think it's very strange," Monique said. "If it's true."
"It's more than just strange," Sally said. "It's an outrage.
Consider the timing. We've got a city like Savannah in terrible trouble right now, with Sealey 3147 the only drug in sight that might keep Savannah from turning into the disaster of the century—and now we find that Sealey is suddenly pulling out. We also know that Sealey has that drug boarded up with patents that nobody can break, so if Sealey doesn't make it, nobody does. Now what does that sound like to you, as a microbiologist with the CDC, at a time like this? Off the record, of course."
Monique sighed. "I don't like it, if that's what you mean-but maybe they have no choice. The drug hits this plague all right, but it also turns up side effects. If they're afraid of the liability—"
"Liability, hell," Sally Grinstone said scornfully.
"Well, what do you think they're after?"
Sally raised her thumb and forefinger and rubbed them together. "Scratch," she said. "Money. Nothing else. Money like you wouldn't believe. I smell blackmail like the stockyards breeze, a squeeze play that's going to make the oil sheiks look like two-bit shills at a carney." She gave Monique a cold look. "Add it up for yourself. When you've got something that a whole lot of people have to have in a hurry—or die—you don't just give it away, not if your name is Sealey. You squeeze it for everything it's worth. You lock it up and wait to see how many are really going to die before you set the price, that's all."
Monique took a deep breath. "Well, that's an interesting allegation," she said. "But why are you coming to me? You're certainly not going to print all that."
"No, I'd be crucified upside down. But maybe there's something here I can print. Something I can't quite get my hands on yet." Sally fixed her large eyes on Monique. "You're familiar with this drug. You ran tests on it before they used it down in Canon City, didn't you?"
"That's right." Monique exchanged glances with Frank. "We tested it here in the lab. Sealey provided a small supply through CDC in Atlanta. We didn't have much time—we already knew the regular antibiotics were not going to work well against the new organism, and we were getting desperate—but we did some very intensive testing."
"And you found it was good. Very good. I saw you on a late news clip on TV when your first results were in."
"The drug was absolutely great," Monique said. "We are getting up to ninety-seven percent kill of the organism with very low concentrations of the drug. I can hardly remember a new drug that looked so extremely good so early. Those tests suggested the stuff would stop infection cold in infected animals, assuming we could get high blood levels fast enough."
"Did that look like a problem?"
"No," Monique said, "but sometimes you just can't. Sometimes a drug is metabolized into something totally inactive just as fast as you stick it into a living system—or sometimes it's cleared so fast by the kidneys or liver that you never get an effective blood level. But when we used this on sick animals, it was just as active there as it was on the culture plates. The only animals we lost on it were the ones that were absolutely terminal before we started the drug. We were really excited— remember how excited we were, Frank? We thought we really had something to nail it to the wall."
"And no sign of side effects?" Sally said.
"No evidence whatever. When the earth-mold antibiotics are toxic, they usually show it in certain characteristic ways in rats or guinea pigs, and there wasn't any sign of trouble. Let me tell you: we were sure enough that it was clean, we had eveiybody in the lab up here taking therapeutic doses for over a week, more than twenty-five people, and we found no signs of toxicity. So finally we had enough left to send down to Carlos for field testing, and he used it in some desperation cases, people who were unquestionably going to die, and it stopped it, with no side effects. So we got FDA clearance to move with it on an emergency basis, and Sealey shipped us a good supply on an experimental protocol. Believe me, they weren't dragging their feet then—they were as excited as we were! They had Mancini, their production man, crawling all over the place. They even sent out that little chemist who developed the drug—what was his name, Frank? Tom Shipman? Funny little guy with hornrimmed glasses—they sent him out to document our testing procedures so they could save time on their end. So we wrapped it all up in ribbons and they moved the drug into Canon City, and Carlos got started with it."
Alan E. Nourse - The Fourth Horseman Page 18
