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by Masha Gessen

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  enzyme deficiencies, Jewish diseases and, [>]–[>], [>]

  epilepsy, [>], [>], [>], [>]–[>], [>] n, [>] n

  estrogen, [>], [>]

  Etcoff, Nancy, [>]–[>]

  eugenics, [>]–[>], [>], [>], [>], [>]

  EuroDNA, [>]

  euthanasia

  Huntington’s disease and, [>], [>]

  in Nazi Germany, [>]–[>], [>], [>]

  exercise/physical activity, [>]–[>], [>], [>], [>] n, [>] n, [>] n

  exon, defined, [>]

  eye color, [>]–[>]

  Faerman, Marina, [>]–[>], [>]–[>]

  familial dysautonomia, [>], [>], [>], [>] n

  family cancer syndrome. see cancer family syndrome

  family information services, [>]–[>], [>] n

  Family TreeDNA, [>], [>]–[>]

  Fanconi’s anemia, [>], [>], [>]–[>]

  fetal hemoglobin, [>]–[>]

  fibromyalgia, [>]–[>]

  folic acid, [>]

  Food and Drug Administration (FDA), [>], [>], [>]

  FORCE (Facing Our Risk of Cancer Empowered), [>]–[>]

  forced sterilization, [>], [>], [>], [>]

  forensics, [>]–[>]

  Foucault, Michel, [>]

  founder effect, [>]–[>]

  Ashkenazi Jews and, [>]–[>], [>], [>], [>]–[>]

  avoiding, [>]

  Cohanim oral tradition/genetic markers and, [>]–[>], [>], [>]–[>], [>], [>], [>], [>]–[>], [>], [>] n

  heterozygote advantage and, [>]–[>]

  Lemba oral tradition and, [>]–[>], [>] n

  nature of, [>]–[>]

  ten lost tribes of Israel and, [>]–[>]

  fragile-child syndrome, [>]–[>]

  framing effect, in medical decision making, [>]–[>]

  Friedman, Sue, [>]–[>]

  frontal lobes, [>]–[>]

  Frudakis, Anthony, [>], [>], [>]

  Furies, The (Hobhouse), [>]–[>]

  Galton, Francis, [>]–[>], [>], [>]

  gangliosides, [>]

  Garber, Judy, [>]–[>]

  Gaucher’s disease, [>], [>], [>], [>], [>], [>]

  Gellhorn, Martha, [>]–[>]

  Gelsinger, Jesse, [>], [>]–[>]

  genealogy, [>], [>]. see also genetic ancestry tests

  gene expression, [>]–[>]

  gene flow, [>]–[>]

  Genelex, [>]

  gene pools, alteration of, [>]–[>]

  gene sequences, [>], [>], [>]–[>]

  gene therapy, [>], [>]–[>], [>], [>] n

  genetic ancestry tests, [>]–[>], [>]–[>], [>]–[>], [>] n

  genetic code, [>]

  genetic counseling, [>], [>]–[>]

  counselor qualifications, [>]

  Dor Yeshorim program and, [>]–[>], [>]–[>], [>]

  economics and, [>]–[>], [>]

  happiness, psychology of, [>]–[>]

  Huntington’s disease and, [>], [>]

  nondirective, [>]–[>], [>]

  posttest, [>]–[>]

  prenatal, [>]–[>], [>]

  preventive surgery and, [>]–[>], [>], [>]

  for previvors, [>]–[>]

  genetic drift, [>]–[>], [>], [>], [>]–[>], [>]–[>], [>], [>]–[>], [>]

  genetic experiments

  mink domestication, [>]–[>]

  mouse domestication, [>]–[>]

  rat domestication, [>]–[>], [>]–[>]

  silver-fox domestication, [>]–[>], [>]

  wolf domestication, [>], [>], [>]

  genetic heritage studies, [>]–[>]

  sample size in, [>]

  time estimates in, [>]–[>]

  genetic mapping, [>]

  genetics-based medicine. see also cancer family syndrome; personalized medicine

  adrenoleukodystrophy, [>], [>]–[>], [>] n

  Amish and, [>], [>], [>], [>]

  “bubble boy” disease and, [>], [>], [>]

  DNA samples in, [>]–[>]

  glutaric aciduria type 1 (GA1), [>]–[>], [>]–[>], [>]

  maple syrup disease and, [>]–[>], [>], [>], [>], [>] n, [>] n

  Old Order Mennonites and, [>]–[>], [>], [>], [>]

  seizure disorder and, [>]–[>], [>]–[>]

  genetic signatures, [>]–[>], [>], [>]–[>]

  genetic testing, see also prenatal screening

  ancestry, [>]–[>], [>]–[>], [>]–[>], [>] n

  on ancient human remains, [>]–[>]

  Dor Yeshorim program, [>]–[>], [>]–[>], [>]

  for gene mutations, [>]–[>], [>], [>]–[>], [>] n

  Jewish attitudes toward, [>]

  newborn genetic screening, [>]–[>]

  population-based screening, [>]–[>]

  predictive, [>], [>]–[>], [>]–[>], [>]–[>], [>] n, [>] n

  preimplantation genetic diagnosis (PGD), [>], [>], [>], [>], [>], [>], [>]–[>], [>], [>] n

  gene transfer, [>]

  genome, [>], [>], [>]

  components of, [>]–[>]

  defined, [>]

  mapping, [>]–[>], [>], [>]

  Germany

  Nazi, [>]–[>], [>]

  Rhine Valley, [>]

  germ-plasm, [>]

  Gessen, Aaron, [>]

  Gessen, Arnold, [>]

  Gessen, Ilya, [>]

  Gessen, Keith, [>]–[>]

  Ghate, Sumedha, [>]–[>], [>], [>]

  glutaric aciduria type 1 (GA1), [>]–[>], [>]–[>], [>]

  glycogen storage disease Type I, [>], [>]

  Gotti, Victoria, [>]

  Green Bay, Wisconsin, cancer family syndrome in, [>]–[>], [>]

  Greenspan, Bennett, [>]–[>]

  Gritsenko, Inga, [>]–[>], [>]

  Gross, Heinrich, [>]–[>], [>]

  Gross, Johann, [>]–[>], [>], [>] n

  guilt, about passing on mutations, [>]

  Hadassah hospital (Israel), [>]–[>], [>], [>], [>]

  hair samples, [>]

  Hammer, Michael, [>], [>], [>], [>]

  Handelin, Barbara, [>], [>]–[>], [>]–[>], [>]–[>]

  haplotypes

  Cohen modal, [>]–[>]

  defined, [>]

  mitochondrial DNA and, [>]

  happiness, psychology of, [>]–[>], [>] n

  Harvard University, [>]

  Hasidic community

  dates before marriage and, [>]

  matchmaking in, [>]–[>], [>]–[>], [>]–[>], [>]

  health insurance, [>]

  heart disease, [>]–[>], [>], [>], [>]–[>] n

  Hehmeyer, Charles, [>], [>]

  hemoglobin studies, [>]–[>]

  hemophilia, [>], [>]–[>]

  hereditary nonpolyposis colorectal cancer, [>]–[>], [>]–[>] n

  heroin addiction, [>]

  heterozygosity, [>]–[>], [>], [>]

  Hirschsprung’s disease, [>], [>]–[>], [>]–[>] n

  Hitler, Adolf, [>], [>]–[>]

  HIV, [>]–[>], [>]–[>]

  Hobhouse, Janet, [>]–[>]

  Holland, BRCA1 gene mutations in, [>]–[>]

  homozygosity, [>], [>], [>], [>] n

  homozygous, defined, [>]

  Hôpital Necker-Enfants Malades (Paris), [>]

  hormone-replacement therapy, [>], [>]–[>], [>]

  host population, [>], [>]–[>]

  human geneticists, [>]–[>], [>], [>], [>], [>], [>], [>], [>]

  Human Genome Project, [>]

  Human Mutation, [>]

  Huntington, George, [>]

  Huntington’s disease, [>], [>]–[>], [>], [>], [>]–[>] n

  attitudes toward being tested for, [>]–[>], [>]–[>], [>]–[>] n

  CAG repeats in, [>]–[>], [>], [>]

  genetic counseling and, [>], [>]

  impact of testing for, [>]–[>]

  predictive testing for, [>], [>]–[>], [>]–[>], [>]–[>], [>] n

  symptoms of, [>]–[>], [>]–[>], [>]–[>], [>]

  true dominance and, [>]–[>], [>] n

&
nbsp; Huntington Society of Canada, [>]

  hypertension

  in genetic experiments, [>]–[>]

  as result of surgical menopause, [>]

  hypnotizability, [>]–[>]

  hysterectomy, [>], [>], [>] n

  Icelanders, [>], [>]

  identical by descent, [>]

  inbreeding, [>], [>], [>]. see also closed groups

  India, family balancing in, [>]

  infanticide, [>], [>]

  infertility, [>]

  information lovers, [>]

  insurance companies, [>], [>]

  intelligence

  Jewish diseases and, [>]–[>], [>] n

  selection for, [>]

  intermarriage

  gene flow and, [>]–[>]

  resistance to, [>]

  intersex newborns, [>]–[>], [>] n

  in vitro fertilization, [>], [>], [>], [>]–[>], [>], [>]–[>]

  Israel

  ancient DNA studies, [>]–[>]

  attitudes toward being tested for hereditary illness, [>]–[>]

  deaf community in, [>]

  genetic studies in, [>]–[>], [>]–[>], [>]–[>], [>], [>], [>], [>], [>]

  ten lost tribes of, [>]–[>]

  Jacob, [>]

  Jacobs, Joseph, [>]

  Jewish diseases. See also Ashkenazi Jews; breast/ovarian cancer-gene mutations

  Canavan, [>], [>], [>], [>]

  defining, [>]

  Dor Yeshorim program and, [>]–[>], [>]–[>], [>]

  founder effect and, [>]–[>]

  Gaucher’s disease, [>], [>], [>], [>], [>], [>]

  genetic drift as cause of, [>]–[>]

  genetic studies on women, [>]

  incidence of genetic diseases, [>]

  intelligence and, [>]–[>], [>] n

  matchmaking and, [>]–[>]

  mutation in connexin 26 gene, [>]

  Niemann-Pick, [>], [>], [>], [>]

  selective advantage and, [>]–[>], [>]–[>], [>]

  Tay-Sachs. see Tay-Sachs

  Kahneman, Daniel, [>], [>]–[>]

  Katzenstein, Howard, [>], [>]–[>], [>]–[>]

  Kazy, Zoltán, [>]

  Kharlamova, Anastasia, [>]–[>]

  Khazars, [>]–[>]

  Kingsbrook Jewish Medical Center (Brooklyn, New York), [>]–[>], [>]

  Köszegi, Botond, [>]

  Kuliev, Anver, [>]–[>], [>]–[>]

  Kurdish Jews, [>]–[>], [>] n

  Laboratory of Behavioral Neurogenomics, [>]–[>]

  Laibson, David, [>]–[>], [>]–[>]

  Lancaster General Hospital (Pennsylvania), [>], [>]

  laryngeal cancer, [>]

  Law for the Prevention of Genetically Diseased Offspring, [>]

  Law of Return, [>]

  Leahy, John, [>]–[>]

  Lee, Derrick Todd, [>]

  Lemba oral tradition, [>]–[>], [>] n

  leprosy, [>], [>] n

  leukemia, [>], [>]

  Levi (son of Jacob), [>]

  Levites, [>]–[>], [>] n

  libido, loss of, [>]–[>], [>], [>]–[>]

  life insurance, [>]

  Lingua Franca, [>]–[>]

  lipid-storage diseases, Jewish diseases as, [>]–[>], [>]–[>]

  Little People of America, [>]

  liver transplants, [>]

  logical memory, [>]

  Lorenzo’s Oil, [>], [>]–[>], [>] n

  low-fat diet, [>], [>]

  lucene, [>]–[>]

  lung cancer, [>], [>] n

  Lykken, David, [>]–[>]

  Lynch, Henry T., [>]–[>], [>]–[>] n

  Lynch, Jean, [>], [>]

  Lynch syndrome, [>]–[>], [>], [>]–[>] n

  malaria, [>], [>], [>]

  malignant melanoma, [>]

  mammography, limitations of, [>]

  maple syrup disease, [>]–[>], [>], [>], [>], [>] n, [>] n

  Markel, Arkady, [>]–[>], [>]

  marker tests, [>]

  marriage counseling, [>]–[>]

  mastectomy

  preventive, [>], [>]–[>], [>]–[>], [>], [>]–[>], [>], [>], [>]–[>], [>], [>], [>], [>]–[>], [>], [>]–[>], [>]–[>], [>] n

  matchmaking, [>]–[>]

  Dor Yeshorim program and, [>]–[>]

  effectiveness of, [>]–[>]

  Hasidic community and, [>]–[>], [>]–[>], [>]–[>], [>]

  Kingsbrook Jewish Medical Center (Brooklyn, New York), [>]–[>], [>]

  Orthodox Jews and, [>]–[>], [>]–[>]

  premarital testing and, [>]–[>], [>]

  matrimonial cancer dynasties, [>]–[>]

  McGinn, Colin, [>]–[>], [>]

  McKusick, Victor, [>]

  medical decision making, [>]–[>]

  medications

  adverse reactions to, [>], [>], [>]–[>] n

  antidepressants, [>]–[>], [>], [>]

  certification for specific purposes, [>]

  chemotherapy, [>], [>]–[>], [>], [>], [>]

  drug-approval process, [>]

  for HIV/AIDS, [>]–[>]

  hormone-replacement therapy, [>], [>]–[>], [>]

  melanoma, malignant, [>]

  memory loss, [>]

  Mendelian inheritance, defined, [>]

  Mendelian Inheritance in Man (McKusick), [>]

  Mendelian laws, [>], [>]–[>], [>]

  Mennonites. see Old Order Mennonites

  menopause, early surgical, [>]–[>], [>]–[>], [>]–[>], [>]–[>], [>] n

  menstruation, delaying onset of, [>], [>] n

  mental retardation

  genetic causes of, [>]–[>], [>], [>] n

  seizure disorders and, [>]

  metabolic derangement, [>]–[>]

  MHL1, [>]

  microcephalic, [>]

  Milgram obedience experiment, [>]

  Miró, Joan, [>], [>]

  miscarriage, [>]

  mitochondrial DNA, [>], [>], [>], [>], [>], [>], [>], [>], [>]

  mitochondrial haplotypes, [>]

  Modern Orthodox, [>]–[>]

  molecular anthropology, [>]–[>], [>], [>]–[>]

  monitors, [>]–[>], [>] n

  monoamine oxidase A (MAOA), [>]–[>], [>]

  morphine, [>]–[>]

  mortality risk, [>]–[>]

  Morton, Caroline, [>], [>]

  Morton, Holmes, [>]–[>], [>]–[>], [>]–[>]

  Amish and, [>], [>]–[>], [>]

  Clinic for Special Children (Strasburg, Pennsylvania), [>]–[>], [>]–[>], [>], [>]–[>], [>], [>]

  newborn genetic screening and, [>]–[>]

  Moser, Hugo, [>], [>]–[>]

  Moses, [>], [>]

  mother-daughter relationships, [>]–[>], [>]–[>]

  mouse domestication, [>]–[>], [>] n

  MRI screening, [>], [>]–[>], [>]–[>], [>], [>]

  MSH2, [>]

  Mucolipidosis Type IV, [>]

  muscle myopathy, [>]

  muscular atrophy, [>]–[>]

  muscular dystrophy, [>]–[>]

  mutation frequency, [>]

  mutation mechanism, [>], [>]

  Myriad, [>]–[>]

  Narod, Stephen, [>]

  Nash, Adam, [>]

  National Cancer Institute, [>]

  National Center for Biotechnology Information, [>]

  National Institutes of Health (NIH), [>], [>]

  nationalism, [>]

  Native Americans, [>]–[>]

  natural assessments, [>]

  natural selection, [>]–[>], [>]–[>]

  Nazi Germany, [>], [>]–[>], [>]

  negative eugenics, [>]

  neuroticism, [>], [>], [>]

  neurotransmitters, [>], [>]

  newborns

  genetic screening, [>]–[>]

  intersex, [>]–[>], [>]

  New England Journal of Medicine, [>]

  New York Times, [>]–[>]

  Niemann-Pick, [>], [>], [>], [>]

  nipples, [>]–[>], [>]–[>]r />
  nondirective genetic counseling, [>]–[>], [>]

  nonsyndromic deafness, [>]

  Northern Ontario Hungtington Disease Resource Centre (Canada), [>]–[>]

  novelty-seeking gene, [>]–[>], [>], [>]

  Odone, Augusto, [>]

  Odone, Lorenzo, [>]–[>]

  Old Order Mennonites, [>]–[>], [>]

  maple syrup disease and, [>]–[>], [>], [>], [>] n

  muscle myopathy and, [>]

  oocytes, [>], [>]

  oophorectomy, [>], [>], [>]–[>], [>]–[>], [>], [>], [>]–[>], [>]–[>], [>]–[>], [>], [>]–[>], [>], [>]–[>], [>]–[>] n

  opiates, [>]

  Oppenheim, Ariella, [>], [>]–[>], [>]–[>]

  ornithine transcarbamylase deficiency, [>]

  Orthodox Jews, [>]

  dates before marriage and, [>]

  dietary limitations, [>]

  matchmaking and, [>]–[>], [>]–[>]

  Modern Orthodox, [>], [>]–[>]

  Tay-Sachs among, [>], [>]

  osteoporosis, [>], [>], [>], [>]

  ovarian cancer. see also breast/ovarian cancer-gene mutations

  BRCA1 and BRCA2 role in, [>]–[>

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