by Greg Gibson
familial breast cancer
growth factors for
pharmacogenetics and
colon cancer
effect of natural selection on
genes and
genetic mutations leading to
lung cancer
pharmacogenetics and
prostate cancer
retinoblastoma
risk factors, calculating
socioeconomic status and
treatments for
canine atopy
carb-blockers
cardiovascular conditions
Carey, Drew
Carrey, Jim
CASP8 (breast cancer protection gene)
CCR5 D32 mutation (HIV-related gene)
CD-CV (common disease-common variant) model (disease susceptibility)
CD4 molecules
CD4+ T-cell population
Celera Genomics
cervical cancer
CFTR (cystic fibrosis gene)
CHEK2 (breast cancer susceptibility gene)
childhood acute lymphoblastic leukemia
Churchill, Winston
citrulline
clinical depression. See depression
CNV (copy number variation)
Cobain, Kurt
cocaine
cocktails of HIV drug treatment
cold chain hypothesis
college students, pace of life for
colon cancer
Comaneci, Nadia
common disease-common variant (CD-CV) model (disease susceptibility)
complex disease. See quantitative genetics
copy number variation (CNV)
corn, subsidized production of
corticosteroids
cortisol
Crohn's disease
Crow, Sheryl
CTLA4 (type 1 diabetes risk gene)
culture, disequilibrium with genes
CXR4 molecules
CYP1A2 gene
CYP2D6 (enzyme type)
cystic fibrosis
d
Darwin, Charles
Davis, Bette
DCC1 (colon cancer susceptibility gene)
deCODE Genetics
dehydration, diabetes and
Delinsky, Barbara
dementia. See also Alzheimer's disease
depression
creative people afflicted with
disequilibrium and
environment and
as epidemic
forms of
genes and
pervasiveness of
pharmacology of
symptoms of
treatments for
Deter, Auguste
developing nations, HIV/AIDS in
diabetes
disequilibrium and
Ella Fitzgerald affected by
forms of
genes and
heart attacks and
insulin regulation and
Jackie Robinson affected by
pathology of
pervasiveness of
symptoms of
thrifty genes hypothesis
treatment for
type 1 diabetes, genes and
type 2 diabetes, genes and
diabetic nephropathy
diabetic neuropathy
diabetic retinopathy
Diamond, Jared
Diana, Princess of Wales
digestive system, inflammatory bowel diseases
disease
determining gene linkages
genetic buffering zone and
threshold of liability for
disease susceptibility models
disequilibrium
diabetes and
between genes and culture
HIV origins and
of immune system
longevity and
mental illness and
DNA repair enzymes
dog breeds, genes and
dopamine
Down syndrome
DR3/DR4 gene combination
DR4/DR9 gene combination
DRB1*15 (multiple sclerosis-related gene)
DRD4 gene
Drosophila
drugs. See also pharmacology; treatment
addictive drugs
AIDS treatments
as cancer treatments
in HIV treatment
for weight control
Duesberg, Peter
Dunedin, New Zealand
dysthymia
dystrophin
e
early onset familial Alzheimer's disease
Ebola
eczema
Elan Pharmaceuticals
Eli Lilly and Company
Emerson, Ralph Waldo
empirical, explained
ENPP1 (obesity-related gene)
environment
asthma, influence on
cancer, role in
depression, role in
gene function, effect on
genetic buffering zone, effect on
imbalance with. See disequilibrium
immune system, influence on
inflammatory bowel diseases, influence on
epidemic
depression as
type 2 diabetes as
epidemiology
Epstein-Barr virus
ESR1 (estrogen receptor gene)
estrogen
breast cancer, effect on
cancer risk, role in
ethnic groups. See racial groups
Evista (raloxifene)
evolutionary, explained
eye cancer (retinoblastoma)
eye color, genes and
f
FADS2 (fatty acid digestion gene)
familial breast cancer
famine survival. See thrifty genes hypothesis
Farley, Chris
fat-burners
feline immunodeficiency virus (FIV)
Fen-Phen
FGFR2 (fibroblast growth factor gene)
Fisher, R. A.
Fitzgerald, Ella
FIV (feline immunodeficiency virus)
5HTP (tryptophan to serotonin conversion drug)
5HTT (serotonin transporter gene)
5HTTLPR (serotonin transporter gene)
fly genetics
Ford, Harrison
forensics, racial profiling
formula-fed infants, insulin levels and
454 Life Sciences
FOXO (longevity-related gene)
Fragile X syndrome
FTO (obesity-related gene)
g
gamma secretase complex
Garbo, Greta
Gardasil
gastrointestinal rotaviruses
Gates Foundation
Genentech
genes. See also alleles; genome; mutations
asthma and
behavior and
brain development and
breast cancer growth factors
cancer ands
depression and
diabetes and
type 1 diabetes
type 2 diabetes
disease susceptibility models
disequilibrium and. See disequilibrium
dog breeds and
early onset familial Alzheimer's disease and
function of
height and weight, effect on
HIV and
human and animal comparisons
imperfection of
insulin and
intelligence and
interrelationships among
late onset Alzheimer's disease and
longevity and
lupus and
mental illness and
multiple sclerosis and
natural selection and
obesity and
pigmentation and
racial groups, differences among
rheumatoid arthritis and
spirituality and
thrifty
genes hypothesis
genetic buffering zone, effect of environment on
genetic drift
genetic mutations. See mutations
genome
changing nature of
personal genome sequencing
sequencing
variation in
genomewide association mapping (GWA)
genomic conflict
Genomics and Personalized Medicine Act of 2006
geographic distribution of asthma rates
gestational diabetes
glucose
The God Gene: How Faith Is Hardwired into Our Genes (Hamer)
Goethe, Johann Wolfgang von
Gorbachev, Mikhail
Gore, Al
gp120 (in viruses)
growth factors for breast cancer. See also risk factors
GSTM1 gene
guanine
Guevara, Ché
GWA (genomewide association mapping)
h
HAART (Highly Active Anti-Retroviral Therapy)
hair color, genes and
Haldane, J. B. S.
hallucinogens
Hamer, Dean
hay fever
HCP5 (HIV-related gene)
heart attacks, diabetes and
heart disease
height, genes and
Hemingway, Ernest
HER2 (receptor)
Herceptin (trastuzumab)
hereditarian fallacy
herpes virus
high blood glucose. See hyperglycemia
Highly Active Anti-Retroviral Therapy (HAART)
histamines
HIV (Human Immunodeficiency Virus). See also AIDS
in developing nations
disease progression to AIDS
genes and
origin of
pathology of
symptoms of infection
transmission methods
treatment for infection
HIV-1
HIV-2
HLA (Human Leukocyte Antigens)
HLA-DRB1 SE (arthritis-related gene)
HLA-G (asthma-related gene)
hookworms
Hormesis Society
Howard Hughes Foundation
HPV (human papillomavirus)
hSerT (serotonin transporter gene)
Hughes, Howard
Human Genome Project
Human Immunodeficiency Virus. See HIV
Human Leukocyte Antigens (HLA)
human papillomavirus (HPV)
humans, genetic differences from animals
Huntington's disease
hygiene hypothesis
hyperadaptationism
hyperglycemia. See also diabetes
hypomania
hypothalamus
i
Iceland, genetic research in
IgE molecules
IGF1 (Insulin like growth factor 1) gene
IL-13 (asthma-related gene)
IL4 cytokine gene
Illumina
imbalance. See disequilibrium
immune system. See also AIDS; HIV; inflammatory diseases
disequilibrium of
hygiene hypothesis
lack of development of
response to pregnancy
type 1 diabetes and
indels
infanticide
infectious disease. See also AIDS; HIV
inflammatory bowel diseases
inflammatory diseases. See also asthma; arthritis
bowel diseases
cold chain hypothesis
hygiene hypothesis
immune disorders
lupus
multiple sclerosis
pathology of
symptoms of
inflammatory immune disorders
influenza
INSIG2 (obesity-related gene)
insulin
production, type 1 diabetes and
regulation
Insulin like growth factor 1 (IGF1) gene
insulin-dependent diabetes mellitus (IDDM). See also type 1 diabetes
intelligence (IQ), genes and
IRAK (Interleukin Receptor Associated Kinases)
islet beta cells
itchy skin. See atopy
j–k
Jackson, Kate
Joel, Billy
Johnson, Magic
Joyner-Kersee, Jackie
juvenile diabetes. See type 1 diabetes
Kafka, Franz
Kaposi's sarcoma
Kennedy, John F.
ketones
kidneys, diabetes and
Kimura, Motoo
kindling theory
KITLG (hair color gene)
Knudson, Alfred
Kraepelin, Emil
Kroc, Ray
l
lactase-phlorizin hydrolase (LPH)
lactose tolerance
Lane-Claypon, Janet
large-effect mutations
late onset Alzheimer's disease
latrine hypothesis
leptin
Lewontin, Richard
A Life Decoded (Venter)
lifespan. See longevity
limbic system
Lincoln, Abraham
linkage mapping
Listeria
longevity
genes and
reproduction and
LPH (lactase-phlorizin hydrolase)
lung cancer
lupus, genes and
lymphomas
m
major depressive disorder
Major Histocompatibility Complex (MHC)
malaria
mammograms
mania
manic depression. See bipolar affective disorder
Maraviroc
March of Dimes Research Foundation
MC1R (weight gain gene)
MCR4 (skin pigmentation gene)
melanocortin
memory loss. See Alzheimer's disease
mental illness. See also bipolar affective disorder; depression
disequilibrium and
genes and
mental retardation
metabolic syndrome
metabolism
disequilibrium of
role in type 2 diabetes
MHC (Major Histocompatibility Complex)
microarray analysis
microcephalin (brain development gene)
Minogue, Kylie
minor depressive disorder
modern life, stress of
molecular clock
molecular existentialism
monoamine oxidase
mood disorders. See depression; mental illness
Moore, Mary Tyler
multifactorial trait. See quantitative genetics
multiple sclerosis, genes and
Murdoch, Iris
muscular dystrophy
mutation-selection-drift balance
mutations
accumulation
to APP (Amyloid Precursor Protein)
cancer and
effect of
familial breast cancer and
large-effect mutations
role in cancer
timing origin of
myelin
n
natural selection
effect on cancer-related genes
longevity and
mutations and
variation and
Neel, Jim
nematode infestation
Newton-John, Olivia
nicotine
non-insulin-dependent diabetes mellitus (NIDDM). See also type 2 diabetes
"non-self" proteins, distinguishing from "self" proteins
The Noonday Demon: An Atlas of Depression (Solomon)
o
O'Connor, Basil
Obama, Barack
obesity. See also weight gain
genes and
insulin regulation and
thrifty
genes hypothsis
OCA2 (eye color gene)
The Omnivore's Dilemma (Pollan)
oncogenes
ORMDL3 (asthma-related gene)
Osmond, Marie
osteoarthritis
p
p53 (tumor suppressor)
The Paranoia Switch (Stout)
pathology
of asthma
of diabetes
of HIV
of inflammatory diseases
Paxil
PC1 (obesity-related gene)
PCP (pneumocystic pneumonia)
PER3 gene
personal genome sequencing
Peter the Great
pharmacogenetics, cancer and
pharmacology of depression
Philadelphia (film)
philanthropy
pigmentation, genes and
plaques in brain
pneumocystic pneumonia (PCP)
polio
hygiene hypothesis
vaccines
Pollan, Michael
polygenic disorder. See quantitative genetics
postnatal depression
postnatal psychosis
PPARG (diabetes-related gene)
pregnancy, immune system responses to
PREP (depression-related gene)
prevention of AIDS
primates, genetic differences from humans
progeria
prolyl endopeptidase
prostate cancer
proto-oncogenes
Prozac
PSEN1 (Alzheimer's disease-related gene)
PSEN2 (Alzheimer's disease-related gene)
psychological diseases
psychotic depression
PTPN22 (type 1 diabetes risk gene)
pyschotherapy in treatment of depression
q–r
quantitative, explained
quantitative genetics, explained
quantitative reasoning for adaptation
racial groups, genetic differences among
racial profiling
raloxifene (Evista)
rare alleles model (disease susceptibility)
Rb (tumor suppressor)
Reagan, Ronald
Relacore
relationships, stress on
repair enzymes in DNA
reproduction, longevity and
respiration, effect of inflammation on
retinoblastoma
Retrovir
retroviruses
rheumatoid arthritis, genes and
Rice, Anne
risk alleles, thrifty genes hypothesis
risk factors for cancer, calculating. See also growth factors
risky behavior, genes and
RNA
Robinson, Jackie
Roosevelt, Franklin Delano
Roosevelt, Teddy
s
Sadat, Anwar
SAMe (tryptophan to serotonin conversion drug)
satiety, regulating
schizophrenia
SCID (Severe Combined Immune Deficiency)
sedentary lifestyles, role in weight gain
