Cancerland
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CHAPTER 6: SNUPPY THE HOUND AND IPSCS
Brooke, James. “Without Apology, Leaping Ahead in Cloning.” New York Times, May 31, 2005. http://www.nytimes.com/2005/05/31/science/without-apology-leaping-ahead-in-cloning.html.
Cutler, D. “Are We Finally Winning the War on Cancer?” Journal of Economic Perspectives 22, no. 4 (2008): 3–26.
Haber, Daniel A., et al. “An Internal Deletion within an 11p13 Zinc Finger Gene Contributes to the Development of Wilms’ Tumor.” Cell 61, no. 7 (1990): 1257–1269.
Holden, C., D. Normile, and C. Mann. “Asia Jockeys for Stem Cell Lead.” Science 307, no. 5710 (2005): 660–664.
Keidan, J. “Medicine and the Media: Sucked into the Herceptin Maelstrom.” British Medical Journal 334, no. 7583 (2007): 18.
Normile, D. “Shinya Yamanaka: Modest Researcher, Results to Brag About.” Science 319, no. 5863 (2008): 562.
CHAPTER 7: PROVOKING A RESPONSE
Bhat, R., and C. Watzl. “Serial Killing of Tumor Cells by Human Natural Killer Cells—Enhancement by Therapeutic Antibodies.” PLOS ONE 2, no. 3 (2007): e326. doi:10.1371/journal.pone.0000326.
Cohen, J. “Building an HIV-Proof Immune System.” Science 317, no. 5838 (2007): 612–614.
Radic, M. “Armed and Accurate: Engineering Cytotoxic T Cells for Eradication of Leukemia.” BMC Biotechnology 12 (2012): 6. doi:10.1186/1472-6750-12-6.
Sedwick, C. “Craig Thompson: The Method to Cancer’s Madness.” Journal of Cell Biology 191, no. 4 (2010): 696–697.
“Vaccines: Calling the Shots.” PBS video, 53:10. http://www.pbs.org/wgbh/nova/body/vaccines-calling-shots.html.
Wailoo, Keith, Julie Livingston, Steven Epstein, and Robert Aronowitz, eds. Three Shots at Prevention: The HPV Vaccine and the Politics of Medicine’s Simple Solutions. Baltimore, M.D.: Johns Hopkins University Press, 2010.
CHAPTER 8: GENE HACKING
Bennett, Jay. “11 Crazy Gene-Hacking Things We Can Do with CRISPR.” Popular Mechanics, January 26, 2016. http://www.popularmechanics.com/science/a19067/11-crazy-things-we-can-do-with-crispr-cas9/.
“Cancer Stat Facts: Melanoma of the Skin.” National Cancer Institute. https://seer.cancer.gov/statfacts/html/melan.html.
Fineran, P., M. Gerritzen, M. Suárez-Diez, T. Künne, J. Boekhorst, S. van Hijum, R. Staals, and S. Brouns. “Degenerate Target Sites Mediate Rapid Primed CRISPR Adaptation.” Proceedings of the National Academy of Sciences of the United States of America 111, no. 16 (2014): 5772.
Horvath, P., and R. Barrangou. “CRISPR/Cas, the Immune System of Bacteria and Archaea.” Science 327, no. 5962 (2010): 167–170.
June, Carl H. “Drugging the Undruggable Ras—Immunotherapy to the Rescue?” New England Journal of Medicine 375 (2016): 2286–2289. doi:10.1056/NEJMe1612215.
Lou, Dianne I., et al. “An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates.” Cell Host & Microbe 20, no. 2 (2016): 178–188.
“6 Year Survivor on Ipilimumab/Yervoy.” Melanoma Research Foundation. March 28, 2011. https://www.melanoma.org/find-support/patient-community/mpip-melanoma-patients-information-page/6-year-survivor-ipilimumab-yervoy.
Staahl, Brett T., et al. “Efficient Genome Editing in the Mouse Brain by Local Delivery of Engineered Cas9 Ribonucleoprotein Complexes.” Nature Biotechnology 35, no. 5 (2017): 431–434. doi:10.1038/nbt.3806.
Walkington, L., P. Lorigan, and S. Danson. “Advances in the Treatment of Late Stage Melanoma: Immunotherapies and Targeted Treatments: The Future of Cancer Therapy.” British Medical Journal 346, no. 7898 (2013): 10.
“World First Use of Gene-Edited Immune Cells to Treat ‘Incurable’ Leukaemia.” Great Ormond Street Hospital for Children. November 5, 2015. http://www.gosh.nhs.uk/news/latest-press-releases/2015-press-release-archive/world-first-use-gene-edited-immune-cells-treat-incurable-leukaemia.
CHAPTER 9: FROM GORY TO GLORY
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Gilpin, S. E., et al. “Bioengineering Lungs for Transplantation.” Thoracic Surgery Clinics 26, no. 2 (2016): 163–171. doi:10.1016/j.thorsurg.2015.12.004.
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White, Mary C., Dawn M. Holman, Jennifer E. Boehm, Lucy A. Peipins, Melissa Grossman, and S. Jane Henley. “Age and Cancer Risk: A Potentially Modifiable Relationship.” American Journal of Preventive Medicine 46, no. 3S1 (2014): S7–15. doi:10.1016/j.amepre.2013.10.029.
INDEX
The index that appeared in the print version of this title does not match the pages in your ebook. Please use the search function on your e-reading device to search for terms of interest. For your reference, the terms that appear in the print index are listed below.
Abbott, Edward Gilbert
Abdus Salam, Mohammad
abortions
ES cells and
HPV vaccine and
abscopal effect
ABVD (adriamycin, bleomycin, vinblastine, dacarbazine)
acquired immunodeficiency syndrome (AIDS)
death related to
epidemic of
as retrovirus
acute leukemia
acute lymphoblastic leukemia (ALL)
adaptation
Addgene
adenovirus
adriamycin. See ABVD
advertising
aging
genetic research and
laughter and
Medicare for
AIDS. See acquired immunodeficiency syndrome
Albert Einstein Cancer Center
Alcor Life Extension Foundation
A
LL. See acute lymphoblastic leukemia
All in One Day
allergies
Allison, James
ALS. See Amyotrophic Lateral Sclerosis
altered polio-cold virus
Alzheimer’s
American Academy of Arts and Sciences
American Cancer Society
American Society of Clinical Oncology
amethopterin. See VAMP
amputations
Amyotrophic Lateral Sclerosis (ALS)
Anaplastic Large Cell Lymphoma of T cells
anatomy
partners in
ancient Greeks
anesthesia
angiogenesis
news of
replication and
animal serum
animal studies
antigen receptors
Chimeric
anxieties
artificial intelligence
Asclepius
Asilomar
Atomic Energy Commission
authenticity
autoimmune disorders
autoimmunity
autologous transplants
STAMP and
Avastin
azidothymidine (AZT)
B cells
antigen receptor of
immunity and
Bach-y-Rita, Paul
bacteria
Baldino, Salvatore
ballot initiative
Baltimore, David
Barclay, Arthur
Barre-Sinoussi, Francoise
Bathory, Elizabeth
Beckwith, Jonathan
Berg, Paul
Bernier, George
beta cells
Big Data
The Biological Basis of Cancer (McKinnell)
biology
biotechnology
Birbaumer, Niels
birth
Bishop, Michael
Bizzozero, Giulio
bleomycin. See ABVD
blindness
blood
AIDS and
ancient Greeks and
animal serum for
bone marrow related to
bone marrow stem cells from
drawing of
microfluidics and
rejuvenation and
blood stem cells
transplant of
variety related to
blood typing
blood-letting
Blueprint Protect
Bluestone, Jeffrey
BMS. See Bristol-Myers Squibb
Bolotin, Alexander
bone
bone marrow
blood related to
for CML
donation of
nuclear reactors and
obsession about
registries for
bone marrow stem cells
from blood
immune system and
location of
bone marrow transplants
for breast cancer
hope from
infections and
Boston Globe
The Boy in the Plastic Bubble
BRAC1
BRAC2
brain cancers
brain cells
brain neuroplasticity
Brave New World (Huxley)
breast cancer
Avastin for
bone marrow transplants for
genetics and
lumpectomy for
STAMP for
breast implants
Bresnahan, Jocelyn
Brigham and Women’s Hospital
Brigham and Women’s Hospital School
Bristol-Myers Squibb (BMS)
Broad Institute
Brokaw, Tom
Buerger’s disease
Burkitt, Denis Parsons
Burkitt’s lymphoma
Burnet, Frank
Burroughs Wellcome
Bush, George H. W.
Bush, George W.
cadavers
Cambridge, Massachusetts
Cambridge University (England)
cancer cell mutations
“cancer control”
The Cancer Genome Atlas Project (TGCA)
cancer institutes
cancer lysis syndrome
cancer stem cells
Cancerland
emotions in
language in
Canellos, George
Cantell, Kari
Caplan, Art
CAR T cells
carcinogens
cardiology
Carl (patient)
Case Western Reserve University
causes
CD4
Celera
cell biology
cell engineering
cell lines
Cellectis
cells. See also specific types
DNA of
genes and
of interest
Maloney retrovirus and
PCD of
replication of
as therapy
Center for Regenerative Medicine and Technology
cervical cancer
Chabner, Bruce
Chang, Susan
Charles II (king)
Charpentier, Emmanuelle
“checkpoint” inhibitors
chemistry
chemists
chemotherapy
bone marrow and
brain cancers and
for CML
cure rate for
death related to
infections from
side effects of
Thomas, E. D., and
Chen, S. Y.
children. See also leukemia
with Burkitt’s lymphoma
malaria in
type I diabetes in
Chimeric antigen receptors
China
chronic injury
chronic lymphocytic leukemia (CLL)
chronic myeloid leukemia (CML)
Gleevec for
Philadelphia chromosome and
Ciba-Geigy
Clem, David
Cleveland Free Clinic
clinical trials
of AZT
CRISPR-Cas9 in
criticism of
for ipilimumab
on KRas
participation in
phases of
push into
randomization
risks in
Clinton, Bill
CLIS. See Complete Locked-In State
CLL. See chronic lymphocytic leukemia
cloning
Cronkite on
Dolly
human embryo, in South Korea
mad cow disease and
Snuppy
clotting system
clustered regularly interspaced short palindromic repeats (CRISPR)
CML. See chronic myeloid leukemia
cocaine
for HIV
cockroaches
Cohen, Stanley
Cohn, Roy
Coley, William
collaboration
for HSCI
from Melton, D.
in science
Collins, Francis
colon cancer
communication
of bone marrow
confidence in
with families
competition
with government
in lab work
among scientists
at Simches Research Center
of space race
in stem cell research
Complete Locked-In State (CLIS)
computational biologist
conception
confidence
in communication
realism and
confirmation
confirmation bias
conspiracy
“control” groups
costs
of cell lines
drug patents and
of drugs
Cowan, Chad
creative perseverance
creativity
discovery and
science and
Crick, Francis
Crile, George, Jr.
Crile, George Washington
crime
CRISPR. See clustered regularly interspaced short palindromic repeats
CRISPR-Cas9
Cronkite, Walter
CTLA-4
culture
at Dana-Farber Cancer Institute
Cunningham, Jim
cure rate, for chemotherapy
cures, hopes about
custom-tailored treatment
cyclamate
cystic fibrosis
dacarbazine. See ABVD
Daley, George
Dana-Farber Cancer Institute
attitude at
culture at
environment at
fear at
mother at
plans at
self-blame at
Dassaett, Jean
Dawkins, Richard
dead tumor
deaths
from acute leukemia
AIDS related to
chemotherapy related to
choice for
decrease in
emotions about
in family
intervention against
motivation from
SIDS
tobacco smoking and
defensive medicine
dementia
deoxyribonucleic acid (DNA)
of cells
CRISPR and
DeVita, Vincent
diabetes
stem cell research on
Dick, John
Dickey, Jay W., Jr.
differentiation
Dimetri, George
discovery
creativity and
from science
distance
DMSO
DNA. See deoxyribonucleic acid
DNA molecule
Maloney retrovirus and
DNA research
DNA sequencers
doctor-as-God identity
doctors, suspicion of
Dolly (cloned sheep)
donor coercion
double helix
Doudna, Jennifer
Down syndrome
Dracula (monster)
drug companies
drug resistance
drugs
commercialization of
“compassionate use” of
costs of
development of
hope about
insurance and
patents for
regulatory approval for
Druker, Brian
phase I of
STI571 and
talk by
Dukakis, Michael
Duke University
economics
psychology and
Edwards, Robert
EGFR. See epidermal growth factor receptor
Eggan, Kevin
egos, of scientists
Egypt
Einstein, Albert
eligibility