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Cancerland

Page 32

by David Scadden


  Elledge, Stephen

  Ellison, Larry

  embryonic stem cell research. See also human embryonic stem (ES) cells

  emotions

  in Cancerland

  about death

  of fraud

  about patient

  about radical mastectomy

  Enard, David

  entitlement

  “entrepreneurial oncology”

  environment

  epidemic, AIDS

  epidemiologists

  epidermal growth factor receptor (EGFR)

  epigenome

  Epstein-Barr virus

  Eron, Lawrence

  ES. See human embryonic stem (ES) cells

  von Eschenbach, Andrew

  Escherichia coli

  Eshhar, Zelig

  ether dome

  ethics

  of science

  Evans, Martin

  evidence-based medicine

  exercise

  expectant mother

  expectations

  from NCI

  experimental treatments

  experiments. See also specific topics

  explorers, scientists as

  exposures. See also radiation exposure

  “extensive learning”

  faith, in science

  families. See also children; mother

  communication with

  death in

  father

  of HSCI

  science and

  of scientists

  family physician

  fantasies

  father

  FDA. See Food and Drug Administration

  fear

  at Dana-Farber Cancer Institute

  monsters related to

  Federal Drug Administration

  fetal and embryonic stem cell research

  fetal cell donation

  Florida Medicare fraud

  Folkman, Judah

  Food and Drug Administration (FDA)

  Ford, Betty

  fraud

  emotions of

  Florida Medicare

  by Hwang

  Fred Hutchinson Cancer Research Center

  Freeman, Gordon

  Freeman, John

  Frei, Emil “Tom”

  Freireich, Emil

  Friend, Charlotte

  “Friend” virus

  Frisan, Jonas

  frogs

  Gurdon and

  Fukuyama, Francis

  funding

  for Druker

  from Geron

  from Harvard University

  for immunotherapy

  investors for

  for Melton, D.

  for stem cell research

  of trainees

  Gallo, Robert

  gamma globulin

  Gardner, Jason

  Gearhart, John

  Gelsinger, Jesse

  gender equality

  breast cancer and

  gene fragments

  gene hacking

  “checkpoint” inhibitors

  CRISPR-Cas9 in

  informatics in

  KRas in

  photon physics in

  Ras mutations and

  TALENS in

  genes

  cancer and

  cells and

  risks and

  gene-splicing

  genetic engineering

  genetic mutations

  genetic research. See also specific topics

  aging and

  double helix in

  genome in

  knockout mouse in

  regulations on

  genetic screening

  genetically engineered drug

  genetics, breast cancer risk and

  Genghis Khan

  genome

  epigenome

  HGP

  size of

  term

  genome science

  genome-editing machine

  germ theory

  Geron

  Gilbert, Walter

  Gill, Parkash

  Gleevec

  glioma

  altered polio-cold virus and

  PVS-RIPO for

  GOSH. See Great Ormond Street Hospital

  government

  competition with

  science and

  graft versus host disease (GvHD)

  CML and

  immune system and

  Graham, Richard

  gratitude, for life

  Graves, Laura

  Great Ormond Street Hospital (GOSH)

  Greeks, ancient

  Gromeier, Matthias

  Grupp, Stephan

  guilt

  Gurdon, John

  GvHD. See graft versus host disease

  Haber, David

  Halsted, William Stewart

  HARRT. See highly active antiretroviral therapy

  Harvard Medical School

  Harvard Stem Cell Institute (HSCI)

  collaboration for

  family of

  first meeting of

  goal for

  innovation at

  interest areas for

  Lab Meeting at

  locations for

  parallel efforts and

  Q at

  recruitment for

  science of

  temperament at

  training at

  women at

  Harvard University

  funding from

  Massachusetts Hall

  Hayflick, Leonard

  Hayflick Limit

  HDC/ABMT. See high-dose chemotherapy and bone marrow transplants

  heart cells

  heart failure

  heart transplants

  hedgehog ligands

  hematology

  hemophilia

  Henrietta Lacks cells

  HER2 receptor

  Herceptin

  herd immunity

  Herodotus

  HGP. See Human Genome Project

  high-dose chemotherapy and bone marrow transplants (HDC/ABMT)

  highly active antiretroviral therapy (HARRT)

  Hippocrates

  history

  HIV

  cell engineering and

  cocaine for

  CRISPR-Cas9 and

  as medicine

  study on

  treatment of

  HIV/AIDS

  AZT for

  HLA. See Human Leukocyte Antigen

  hobbies

  Hochedlinger, Konrad

  Hodgkin’s lymphoma

  ABVD for

  hope

  for adults

  from bone marrow transplants

  from Gleevec

  promises and

  of science

  for tools

  understanding and

  Horwitz, Jerome

  Howard Hughes Medical Institute

  HPV. See human papillomavirus

  HPV vaccine

  HSCI. See Harvard Stem Cell Institute

  HTLV-1

  HTLV-2

  human eggs

  human embryo cloning

  human embryonic stem (ES) cells

  Melton, D., and

  Thomson and

  human gene therapy

  Human Genome Project (HGP)

  Human Leukocyte Antigen (HLA)

  human life span

  human papillomavirus (HPV)

  human pluripotent stem cells

  iPSC as

  humanity

  authenticity of

  humor

  Huxley, Aldous

  Hwang Woo-suk

  hypermutation

  idealism, in medical school

  immune cell lymphocytes

  immune cells

  immune disorders

  immune response

  beta cells and

  in immune system

  immune system

  abscopal effect and

/>   bone marrow stem cells and

  clotting system and

  curiosity about

  GvHD and

  immune response in

  infectious diseases and

  liver disease and

  malignancies and

  memory for

  of mice

  pathway of

  postoperative infections and

  proteins and

  targets of

  thymus and

  tolerance and

  transplants and

  understanding about

  work of

  immunity

  autoimmunity

  B cells and

  herd

  from influenza viruses

  immunology

  immunostimulant

  immunotherapy

  funding for

  In His Image: The Cloning of a Man (Rorvik)

  in vitro fertilization (IVF)

  infertility and

  in vitro gametogenesis (IVG)

  induced pluripotent stem cells (iPSC)

  Type 2 diabetes and

  infections

  from acute lymphoblastic leukemia

  bone marrow and

  bone marrow transplants and

  cancer related to

  from chemotherapy

  immune disorders and

  in news

  viral

  infectious disease

  immune system and

  infertility

  influenza viruses

  informatics

  injury, chronic

  insulin

  insurance

  Intel

  interferon

  internship

  home during

  location for

  routine of

  interventions

  against deaths

  side effects of

  intuition

  investors

  angiogenesis and

  “entrepreneurial oncology” and

  interferon and

  ipilimumab

  iPSC. See induced pluripotent stem cells

  Isaacs, Alick

  Israel

  IVF. See in vitro fertilization

  IVG. See in vitro gametogenesis

  Jacobson, Leon

  Jaenisch, Rudolph

  James, William

  Jansen, Ruud

  Jews

  Jolie, Angelina

  June, Carl

  background of

  CLL and

  results of

  Kaposi’s sarcoma

  Kathy

  Kennedy, John F.

  kidneys

  kinases

  kindness

  Kirsten, W. H.

  Kolata, Gina

  Koonin, Eugene

  KRas

  Kuhn, Thomas

  Kuter, David

  lab work

  competition in

  in immunology

  for Mahmoud

  Laetrile

  Lajtha, Lazslo

  Lamarck, Jean-Baptiste

  Langer, Robert

  language

  lasers

  laughter

  aging and

  culture and

  Lazarus, Hillard

  Lederberg, Joshua

  Lehman, Betsy

  Lercher, Martin

  Letton, A. Hamblin

  leukemia. See also chronic myeloid leukemia

  ALL

  CLL

  retroviruses related to

  stem cells and

  VAMP for

  Levi-Montalcini, Rita

  life

  appreciation for

  gratitude for

  human life span

  of service

  Yeats and

  life science

  life-affirmation

  limitations

  of treatments

  Lin

  Lindenmann, Jean

  Link, Nathan

  Lipscomb, Stephanie

  liver

  liver cancer

  liver disease

  loss. See also deaths

  attachment and

  lumpectomy

  lung cancer

  surgeries for

  lung resections

  Lydon, Nick

  lymphocytes

  CLL

  mutations of

  receptor genes and

  “tolerance of self” and

  lymphoid cells

  lymphoma

  Burkitt’s

  Hodgkin’s

  non-Hodgkin’s

  lysis

  Macklis, Jeff

  macroeconomics

  mad cow disease

  Magenta Therapeutics

  Mahmoud, Adel

  Main, Joan M.

  malaria

  in children

  malignancies

  Gleevec for

  immune system and

  mutations related to

  surgeries for

  viruses in

  Maloney retrovirus

  marriage

  Massachusetts General Hospital (MGH)

  Massachusetts Hall

  mastectomy

  Max Planck Institute for Infection Biology

  McBeth, John

  McCulloch, Ernest

  McKinnell, Robert G.

  measles

  meat

  mechanics, of cancer

  medical advance process

  medical school

  medical system

  Medicare

  medicines

  defensive

  evidence-based

  HIV as

  plant-derived

  precision

  regenerative

  science compared to

  melanoma

  Melton, Douglas

  collaboration from

  ES cells and

  meeting with

  as scientist

  Melton, Sam

  memory

  for immune system

  messenger RNA

  metabolic disorder

  metabolism

  metaphors

  metastatic cancer

  methotrexate. See VAMP

  Meyer, Robert

  MGH. See Massachusetts General Hospital

  mice

  cloning of

  genomes of

  immune system of

  model of

  Michor, Franziska

  microbiology regulations

  microfluidics

  military research

  Miller, Jacques

  Mojica, Francisco

  molecular biology

  DNA molecule in

  post-doctoral fellow in

  molecules

  DNA

  mononucleosis

  Montagnier, Lou

  mother

  at Dana-Farber Cancer Institute

  death of

  expectant

  lung resections of

  optimism about

  options for

  pain of

  surgeries for

  treatments for

  motivation

  mouse embryonic stem cells

  multiple sclerosis (MS)

  muscular dystrophy

  mutations

  benefits of

  of cancer cells

  differentiation and

  of lymphocytes

  malignancies related to

  Napster

  NASA. See National Aeronautics and Space Administration

  Nathan, David

  National Aeronautics and Space Administration (NASA)

  National Cancer Institute (NCI)

  expectations from

  Rosenberg at

  National Institutes of Health

  natural histories

  natural selection

  NCI. See National Cancer Institute

  Neumann, Ernst

  neurons

  neuroplasticity
, of brain

  The New York Times

  news

  of angiogenesis

  about carcinogens

  cloning in

  dead tumor in

  about DNA molecule

  genetically engineered drugs in

  infections in

  Nixon, Pat

  Nixon, Richard

  Nobel prize

  in economics

  for Gurdon

  for Lederberg

  non-Hodgkin’s lymphoma

  Noon, Leonard

  Novartis

  Nowell, Peter

  nuclear reactors

  nuclear transfer

  nucleases

  Obokata, Haruko

  Occam’s razor

  odors

  oncogenes

  oncology. See also specific topics

  optimism

  optimism bias

  organic chemistry

  organoids

  Orkin, Stuart

  “orphan drug”

  Osteen, Robert

  Ott, Herald

  ovarian cancer

  paclitaxel. See Taxol

  pain

  in sickle-cell anemia

  pancreas

  pancreatic cancer

  Pappenheim, Artur

  Pappenheim, Josef

  paradigm shift

  paralysis, partial

  Pardoll, Drew

  Parker, Sean

  Parker Institute for Cancer Immunotherapy

  Parkinson’s disease

  Pasteur, Louis

  patents

  for drugs

  for gene fragments

  patient-centered care

  patients

  Carl

  eligibility of

  emotions about

  options for

  research by

  PCD. See programmed cell death

  Petrov, Dmitri

  Peyton Rous, Francis

  p53 gene

  pharmaceutical companies

  pharmacologists

  pharmacology

  Philadelphia chromosome

  photon physics

  physician

  interest as

  role model of

  plant-derived medicines

  poetry

  pollution

  postoperative infections

  poverty

  power

  Precision Medicine Cohort Project

  precision medicines

  prednisone. See VAMP

  Prehn, R. T.

  “professional distance”

  “progenitor” cells

  programmed cell death (PCD)

  prostate cancer

  proteins

  CTLA-4

  immune system and

  kinases

  Provenge

  pseudoscience

  psychology

  Ptashne, Mark

  public dissection

  public relations

  publishing

  PVS-RIPO

  Q

  radiation exposure

  of Margaret

  stem cells and

  radiation therapy side effects

  radical mastectomy

  randomization

  proof and

  randomness, receptor genes and

  Rappeport, Joel

  Ras mutations

  Reagan, Ronald

  realism

  real-time imaging

  receptor genes

  viruses and

  recognition

  recombinant DNA research

  ban on

  reductionism

  regeneration

  EGFR in

  of stem cells

  of tissues

  regenerative medicine

  Herodotus and

  regulations

  from FDA

  on gene research

  of science

  stem cell clinics and

  regulatory approval, for drugs

  rejuvenation, blood and

 

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