It Takes a Genome: How a Clash Between Our Genes and Modern Life is Making Us Sick

by Greg Gibson

  Selective Estrogen Receptor Modifiers (SERMs)

  selective serotonin reuptake inhibitors (SSRIs)

  "self" proteins, distinguishing from "non-self" proteins

  senile dementia. See Alzheimer's disease; dementia

  sensitization

  sequencing. See genome sequencing

  SERMS (Selective Estrogen Receptor Modifiers)

  serotonin

  genes and

  Severe Combined Immune Deficiency (SCID)

  Shields, Brooke

  sickle cell anemia

  simian immunodeficiency virus (SIV)

  Simon, Carly

  single gene model (disease susceptibility)

  single nucleotide polymorphisms (SNPs)

  SIV (simian immunodeficiency virus)

  6-MP (cancer drug)

  skin pigmentation, genes and

  skin rashes. See atopy

  SLC24A4 (eye color gene)

  SLC6A4 (serotonin transporter gene)

  sleeping sickness

  small effect model (disease susceptibility)

  Small Ubiquitin-related Modifier (SUMO)

  smallpox

  Smith, Jaclyn

  SNPs (single nucleotide polymorphisms)

  socioeconomic factors

  cancer and

  weight gain and

  Solomon, Andrew

  Somers, Suzanne

  Speakman, John

  spirituality, genes and

  SSRIs (selective serotonin reuptake inhibitors)

  staufen

  Stefansson, Kari

  Steinem, Gloria

  steroids. See corticosteroids

  Stout, Martha

  Strachan, David

  stress

  depression, role in

  responses

  suicide, genes and

  SUMO4 (type 1 diabetes risk gene)

  survivability of breast cancer

  symptoms

  of asthma

  of depression

  of diabetes

  of HIV infection

  of inflammatory diseases

  t

  T-cell counts

  T-cells

  asthma role of

  blood brain barrier

  in HIV pathology

  tamoxifen

  Tan, Amy

  tangles in brain

  Tao (protein)

  TCF7L2 (diabetes-related gene)

  TGFβ (growth factor gene)

  Thorpe, Ian

  threshold of liability

  thrifty genes hypothesis

  thymidine

  thymus

  TMPT gene

  Tolstoy, Leo

  Tracy, Spencer

  trastuzumab (Herceptin)

  treatment

  for AIDS

  for asthma

  for depression

  for diabetes

  for HIV infection

  tricyclic antidepressants

  tryptophan

  tuberculosis

  tumor suppressors

  type 1 diabetes

  genes and

  type 2 diabetes compared

  type 2 diabetes

  genes and

  type 1 diabetes compared

  weight gain and

  tyrosine kinase inhibitors

  u–v

  Ulcerative Colitis

  unipolar affective disorder

  Uplift (Delinsky)

  urine, diabetes and

  vaccines

  HPV vaccine

  polio vaccines

  Van Dyken, Amy

  variation, natural selection and

  vascular dementia

  Venter, Craig

  viral set point

  virtual worlds

  viruses. See also HIV

  cancer-causing viruses

  prevalence of

  vision problems, diabetes and

  vitamin D3, sunlight and

  VMAT2 (spirituality-related gene)

  w–z

  weight, genes and

  weight gain, reasons for. See also obesity

  Wellbutrin

  Wellcome Trust

  The West Wing (television program)

  Williams, Tennessee

  "Women in Film" video clip

  Wright, Sewall

  Yersinia

  young people, pace of life for

  Ziagen

  Zidovudine

  ZNRD1 (HIV-related gene)

  Zoloft